Glaxo adds heart warning to ADHD drug

scotty · 08-21-2006, 02:03 PM

http://today.reuters.com/news/articl...EPRESSANTS.xml

Glaxo adds heart warning to ADHD drug
Mon Aug 21, 2006 1:37pm ET

WASHINGTON (Reuters) - GlaxoSmithKline Plc (GSK.L: Quote, Profile, Research) (GSK.N: Quote, Profile, Research) has said it will add a boxed warning about possible heart risk to its attention deficit hyperactivity drug Dexedrine, according to a letter posted to the U.S. Food and Drug Administration's Web site on Monday.

In its letter, the drugmaker said it was adding the warning "in response to a Food and Drug Administration ... request sent to the manufacturers of all CNS (central nervous system) stimulant products approved for the treatment of ADHD."

LCrawford67 · 08-21-2006, 02:16 PM

How big of them! And how nice of the FDA to make such a "request."

Iksfreundin · 08-21-2006, 02:27 PM

Yes indeed: "please inform your patients that serious heart problems and death may result. Unless you don't want to. You don't have to. But you should. But we won't regulate it or anything."

Delynbetter · 08-21-2006, 02:47 PM

I've decided that I have finally reached a point where I have no comments left. (That will change tomorrow, but for now...)

Lilly · 08-21-2006, 03:05 PM

My son in law is now off them and doing well. Chelsea told me he started right before they got married and I was scared. I told her all I knew, but then left it alone. I told her if his personality changed somethings up. And changed it did. He did not remember one holiday to her. No cards or gifts. She would call me crying. Mr. Romantic was gone.Then he stopped remembering anything at all. He got his dose doubled.

Now they were fighting all the time, he hated his job. He had worked his way up and was in management and doing really well for young man his age. He wanted to quit one day and she made him go in and do it right and give notice and they told him he was fired, he was under survelleince for embezzlement. He admitted to it and had to go file a police report. 1,500 dollars. Now she knew where he was when he would just dissapear and how he was able to get all these nice little things he wanted, they could not afford.

He was a good clean kid before this. I came here and got directions on tapering and what to expect for them and guided them along. He's working in a car dealership now and they are making it, but I don't see much hope for future for him there. He's very frightened about what happened to him and very sorry and Chelsea is rightfully disillussioned about marriage now. They have not even had there second anniversary yet.

I'm hoping from now out things get better for them.
Lilly

seahorse18 · 08-22-2006, 10:17 AM

Lilly -

What a sad story! If only more people could/would put two and two together in regards to these drugs. My hope is your family will recover from this awful drug fall-out. Something needs to be done about these drugs - and quick, before more people's lives are destroyed.

rdjanis · 08-22-2006, 10:25 AM

Sorry to hear this Lilly!!

seahorse18 · 08-22-2006, 10:29 AM

I noticed that this was only a small blurb, so far, in the news industry. However (as I just posted), I have watched two segments (so far) about
"Post Wedding Day Blues".

People seem to gravitate towards news of all sorts of new "psychiatric disorders", but when it comes to heeding the warnings about serious side-effects of drugs prescribed for these new "disorders", they are strangely silent and unresponsive.

Lilly · 08-22-2006, 07:37 PM

I think they are going to be fine. He was a very intent young men before this and he is getting that back again. Just a lot for a young couple to go through. I'm glad I knew about stuff and was able to guide it somewhat when things got really bad.

Thank you both!
Lilly

08-21-2006, 02:03 PM	#1
scotty Administrator Join Date: Feb 2004 Location: new jersey Posts: 47,007	Glaxo adds heart warning to ADHD drug http://today.reuters.com/news/articl...EPRESSANTS.xml Glaxo adds heart warning to ADHD drug Mon Aug 21, 2006 1:37pm ET WASHINGTON (Reuters) - GlaxoSmithKline Plc (GSK.L: Quote, Profile, Research) (GSK.N: Quote, Profile, Research) has said it will add a boxed warning about possible heart risk to its attention deficit hyperactivity drug Dexedrine, according to a letter posted to the U.S. Food and Drug Administration's Web site on Monday. In its letter, the drugmaker said it was adding the warning "in response to a Food and Drug Administration ... request sent to the manufacturers of all CNS (central nervous system) stimulant products approved for the treatment of ADHD." __________________ AKA Laurie "Faith is taking the first step even when you don't see the whole staircase." MLK

08-21-2006, 02:16 PM	#2
LCrawford67 Moderator "Everybody poops" Join Date: Mar 2006 Location: Ohio Posts: 34,484	Re: Glaxo adds heart warning to ADHD drug How big of them! And how nice of the FDA to make such a "request." __________________ aka LC aka Laurie C. Paxil, 20 mg since 1997, for IBS Two unsuccessful attempts to quit. Started tapering 11/27/06 PAXIL FREE 12/29/07 Today is the best day, EVER!

08-21-2006, 02:27 PM	#3
Iksfreundin "Dancing Queen" Join Date: May 2006 Location: USA Posts: 3,585	Re: Glaxo adds heart warning to ADHD drug Yes indeed: "please inform your patients that serious heart problems and death may result. Unless you don't want to. You don't have to. But you should. But we won't regulate it or anything." __________________ 95' - started paxil, 20 mgs; up to 30. two ct's, then 60 mgs for years. 40 mgs in '02, poop-out in '05 start taper= 5/8/06 at 20 = 6/17/06 at 15 = 8/8/06 at 10 = 10/15/06 at 5 = 12/14/06 Paxil free as of 3/8/08 (drops were done gradually ) Smoke-free as of 2/27/08 Still doing well, no smoking yet and I haven't been hospitalized (well, I DID have my gallbladder removed) - 3/16/2012 "You, however, smear me with lies; you are worthless physicians, all of you!" Job 13:4, KJV Bible

08-21-2006, 02:47 PM	#4
Delynbetter Join Date: May 2005 Location: Texas Posts: 10,769	Re: Glaxo adds heart warning to ADHD drug I've decided that I have finally reached a point where I have no comments left. (That will change tomorrow, but for now...) __________________ Diagnosed anxiety/panic disorder without agoraphobia 1989. Talk/music therapy. Major anxiety and mild depression in 2004 from situational stressors. Began Paxil CR 25mg, 10/04. Quit cold-turkey 5/5/05 as demanded by doctor. Found paxilprogress 5/17/05. Began Paxil CR 12.5mg 5/17/05. Weaned 4 1/2 months. During taper - anx/panic/depression, manic episodes, agoraphobia, suicidal ideation, many other physical symptoms. Paxil-free 10/2/05.

08-21-2006, 03:05 PM	#5
Lilly Join Date: Jun 2002 Location: Northwest Posts: 7,188	Re: Glaxo adds heart warning to ADHD drug My son in law is now off them and doing well. Chelsea told me he started right before they got married and I was scared. I told her all I knew, but then left it alone. I told her if his personality changed somethings up. And changed it did. He did not remember one holiday to her. No cards or gifts. She would call me crying. Mr. Romantic was gone.Then he stopped remembering anything at all. He got his dose doubled. Now they were fighting all the time, he hated his job. He had worked his way up and was in management and doing really well for young man his age. He wanted to quit one day and she made him go in and do it right and give notice and they told him he was fired, he was under survelleince for embezzlement. He admitted to it and had to go file a police report. 1,500 dollars. Now she knew where he was when he would just dissapear and how he was able to get all these nice little things he wanted, they could not afford. He was a good clean kid before this. I came here and got directions on tapering and what to expect for them and guided them along. He's working in a car dealership now and they are making it, but I don't see much hope for future for him there. He's very frightened about what happened to him and very sorry and Chelsea is rightfully disillussioned about marriage now. They have not even had there second anniversary yet. I'm hoping from now out things get better for them. Lilly __________________ 1 .5 Xanax a day for one month. C/T. Same year, 3 .5 mil Xanax a day, 4 by the end. Pooped out on me. 1 1/2 years on the drug. Doctors taper. Very bad w/d. 9 months later took 10 mg Paxil and my Xanax w/d dissapeared. On 20 mg by end. Pooped out on me. C/T then restarted it again after 3 days and big blow up. 6 months taper, never feeling much better. 2 1/2 years solid w/d then sporadic stuff for 5 years. Completely recovered! Drug free since June 2001.

08-22-2006, 10:17 AM	#6
seahorse18 Join Date: Aug 2005 Posts: 301	Re: Glaxo adds heart warning to ADHD drug Lilly - What a sad story! If only more people could/would put two and two together in regards to these drugs. My hope is your family will recover from this awful drug fall-out. Something needs to be done about these drugs - and quick, before more people's lives are destroyed.

08-22-2006, 10:25 AM	#7
rdjanis "has a lavender scented keyboard" Join Date: Mar 2004 Location: Ontario Posts: 22,214	Re: Glaxo adds heart warning to ADHD drug Sorry to hear this Lilly!! __________________ Rita

08-22-2006, 10:29 AM	#8
seahorse18 Join Date: Aug 2005 Posts: 301	Re: Glaxo adds heart warning to ADHD drug I noticed that this was only a small blurb, so far, in the news industry. However (as I just posted), I have watched two segments (so far) about "Post Wedding Day Blues". People seem to gravitate towards news of all sorts of new "psychiatric disorders", but when it comes to heeding the warnings about serious side-effects of drugs prescribed for these new "disorders", they are strangely silent and unresponsive.

08-22-2006, 07:37 PM	#9
Lilly Join Date: Jun 2002 Location: Northwest Posts: 7,188	Re: Glaxo adds heart warning to ADHD drug I think they are going to be fine. He was a very intent young men before this and he is getting that back again. Just a lot for a young couple to go through. I'm glad I knew about stuff and was able to guide it somewhat when things got really bad. Thank you both! Lilly __________________ 1 .5 Xanax a day for one month. C/T. Same year, 3 .5 mil Xanax a day, 4 by the end. Pooped out on me. 1 1/2 years on the drug. Doctors taper. Very bad w/d. 9 months later took 10 mg Paxil and my Xanax w/d dissapeared. On 20 mg by end. Pooped out on me. C/T then restarted it again after 3 days and big blow up. 6 months taper, never feeling much better. 2 1/2 years solid w/d then sporadic stuff for 5 years. Completely recovered! Drug free since June 2001.

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