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Old 08-22-2006, 02:24 PM   #1
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Europe's top drugmaker GlaxoSmithKline to open new Irish R&D centre in Cork

Europe's top drugmaker GlaxoSmithKline to open new Irish R&D centre in Cork

http://www.finfacts.com/irelandbusin...10006982.shtml

Europe's top drugmaker GlaxoSmithKline to open new Irish R&D centre in Cork
By Finfacts Team
Aug 20, 2006, 16:39


Jean-Pierre Garnier, Chief Executive Officer
Europe's top drugmaker GlaxoSmithKline (GSK), which has an estimated seven per cent of the world's pharmaceutical market, has agreed to makea multi-million-euro investment in a research and development centre in Cork.

The Sunday Business Post reports today that details of the major project, which will result in the creation of highly-skilled research jobs, will be announced on Tuesday by Minister for Enterprise and Employment Micheál Martin. It will be grant supported by IDA Ireland and Science Foundation Ireland, and was described by sources as ‘‘very significant’’.

GSK will work with the Alimentary Pharmabiotic Centre at University College Cork, which researches the role of bacteria in diseases, including cancer and Crohn’s disease.


GSK employs a total of over 1,400 people in Ireland with manufacturing and R&D facilities in Ringaskiddy, Cork and Dungarvan, Co. Waterford and sales and marketing functions in Dublin.
GSK Cork
Established in 1974, the Cork plant is a strategic global new product introduction site within GSK’s manufacturing network and is currently the sole production site for a number of the Group’s top selling drugs such as Seroxat which is an anti-depressant, Avandia which addresses Type 2 diabetes and Coreg which treats serious heart conditions.

In 2004, an investment of €34m in R&D by the Group was announced for the Cork site. This included an €8m expansion of its existing R&D chemical pilot plant, €7m investment in a new R&D physical property laboratory and a €19m investment in a new pharmaceutical R&D pilot facility focusing on specialist milling. Cork is the sole manufacturing site within GSK to have this technology which is applicable to several new products in the Group’s pipeline.


Dungarvan Sites
GSK has two manufacturing plants based in Dungarvan, Co. Waterford. One is a global pharmaceutical manufacturing facility engaged in the production of a range of over the counter pharmaceuticals. Products include Panadol, Coldrex, Solpadeine and Panadol Extra. The other is an oral care facility manufacturing products such as dental fixative and denture cleaning tablets.


GSK produces medicines that treat six major disease areas – asthma, virus control, infections, mental health, diabetes and digestive conditions. In addition, it is a leader in the important area of vaccines and are developing new treatments for cancer. GSK employs 110,000 employees in 80 countries.


Aims of University College Cork's Alimentary Pharmabiotic Centre

To investigate the means by which intestinal bacteria influence health and disease

· To develop new therapies for lifelong debilitating gastrointestinal diseases such as gastroenteritis, ulcerative colitis, and Crohn’s disease

· To explore commercial opportunities in both the pharma and functional food sector and to position Ireland at the forefront of this exciting new area

· To attract the brightest and most enthusiastic students to our Postgraduate Programme and to deliver a training programme renowned for its excellence

· To provide a resource for education and training of industry personnel by delivering a high level of expertise suited to both food and pharma

· To actively promote communication with government, Irish and international industry and the public, in particular schools and young people, on issues such as gastrointestinal disorders, probiotics and functional foods as well as keeping the public abreast of new therapeutic agents, ongoing clinical trials and exciting new research findings

Prof. Fergus Shanahan, Director, Alimentary Pharmabiotic Centre at UCC says:

Science today is about shared minds; it is about collaborations and multidisciplinary teams. It is about people allowed to express themselves as individuals but working together. This is the essence of the Alimentary Pharmabiotic Centre. A hybrid team of clinicians and basic scientists from disparate traditional disciplines has come together to explore the molecular mechanisms by which food-grade bacteria and resident bacteria within the gut interact with the host. The team spans different faculties (medicine, science and food science and nutrition) and multiple departments within the university. It includes colleagues within Teagasc, Moorepark and embraces industry-academe collaboration. The foundation industry alliance for the Alimentary Pharmabiotic Centre is with Alimentary Health Ltd in association with the Procter and Gamble Company. It is anticipated that additional campus companies will emerge from the centre and new partnerships with Irish and multinational companies will also be promoted.

The intestinal bacterial flora is predominantly a health asset and occasionally a liability. Manipulation of the flora to enhance this asset and offset any liabilities is emerging as a realistic therapeutic strategy in various diseases that affect human and animal welfare. These diseases include infections, inflammatory bowel disease and colon cancer. Manipulation of the flora can be achieved safely with food-grade bacteria and with functional food ingredients that influence intestinal bacteria. In addition, the intestinal flora represents a rich repository of substances that can be mined for discovery of novel drugs such as anti-inflammatories and anti-microbials. By understanding bacterial signalling and interactions with the host immune system, new molecular targets can be exploited for drug development (‘from bugs to drugs’). Thus, the work of the Alimentary Pharmabiotic Centre is of tangible importance to several industries including human health maintenance, agriculture and animal husbandry and is pitched at the interface of both the food pharmaceutical sectors.
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Old 08-22-2006, 03:47 PM   #2
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Re: Europe's top drugmaker GlaxoSmithKline to open new Irish R&D centre in Cork

Should we send a welcome wagon?
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Old 08-22-2006, 06:04 PM   #3
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Re: Europe's top drugmaker GlaxoSmithKline to open new Irish R&D centre in Cork

Quote:
Originally Posted by Delynbetter
Should we send a welcome wagon?
Oh, I believe we should!!!
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Old 08-23-2006, 06:56 PM   #4
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Re: Europe's top drugmaker GlaxoSmithKline to open new Irish R&D centre in Cork

My daughters and I visited Ireland two years ago and we were charmed by Cork. However, reading the list of GSK sites in Ireland makes me sick to my stomach. I knew that Ireland's economy was growing fast; I believe faster than most of Europe. Too bad that a major contributor to this economic growth is the pharma scum. I wish they would all get back to solving the real problems we have - how about the super bacteria that seem like they are getting ready to take over - can't they work on that for a change?????
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