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Old 01-18-2008, 11:02 AM   #1
Bern
 
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Does anyone know what nutrients Paxil depletes?

Does anyone know what nutrients Paxil depletes?

I took my grandmother to the chiropracter, and I was reading a handbook of health information. In that handbook, it said that prescription drugs deplete nutrients.
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I have been taking Anafranil since 2005.

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Old 01-18-2008, 11:06 AM   #2
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Re: Does anyone know what nutrients Paxil depletes?

Antidepressant Drugs

Includes drugs used to stimulate the mood of a depressed patient. Some are used in eating disorders, treating obesity, and panic disorders. Drugs include tricyclic and SSRI medicines such as Amitriptyline, Elavil. Trazodone, Desipramine, Pamelor, Nortriptyline, Serzone, Paxil, Prozac, Zoloft and Imipramine.
B-Complex Vitamins: Additional B-\itamins are critical when taking antidepressants for short or extended periods. Vitamin B12 and folic acid are especially necessary. There may also be an additional need for riboflavin (B2).
Selenium: Stores of selenium are compromised with extended use of these drugs. A suggested supplementation dose would be 50 to 100 micrograms daily.
Zinc: Depletion of this antioxidant can slow wound healing reduce the sense of taste. Supplement with a dose of 10-35 mg per day.
L-Gluthathione: An important amino acid that decreases free radicals and helps to protect your liver.
Calcium/Magnesium: Take for nutritional support, along with additional minerals.
Vitamin C

Here's the entire article:

http://www.alive.com/3761a1a2.php?su...read_cramb=181
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Old 01-18-2008, 11:29 AM   #3
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Re: Does anyone know what nutrients Paxil depletes?

Quote:
Selenium: Stores of selenium are compromised with extended use of these drugs.
I looked up Selenium on wikipedia.....http://en.wikipedia.org/wiki/Selenium
This is what I found.....
Quote:
Controversial health effects

Cancer

Several studies have suggested a link between cancer and selenium deficiency.A study conducted on the effect of selenium supplementation on the recurrence of skin cancers did not demonstrate a reduced rate of recurrence of skin cancers, but did show a significantly reduced occurrence of total cancers.[22] Dietary selenium prevents chemically induced carcinogenesis in many rodent studies.[23] In these studies, organic seleno-compounds are more potent and less toxic than selenium salts (e.g., selenocyanates, selenomethionine, selenium-rich Brazil nuts, or selenium-enriched garlic or broccoli). Selenium may help prevent cancer by acting as an antioxidant or by enhancing immune activity. Not all studies agree on the cancer-fighting effects of selenium. One study of naturally occurring levels of selenium in over 60,000 participants did not show a significant correlation between those levels and cancer.[24] The SU.VI.MAX study[25] concluded that low-dose supplementation (with 120 mg of ascorbic acid, 30 mg of vitamin E, 6 mg of beta carotene, 100 g of selenium, and 20 mg of zinc) resulted in a 31% reduction in the incidence of cancer and a 37% reduction in all cause mortality in males, but did not get a significant result for females.[26] The SELECT study[27] is currently investigating the effect of selenium and vitamin E supplementation on incidence of prostate cancer. However, selenium has been proven to help chemotherapy treatment by enhancing the efficacy of the treatment, reducing the toxicity of chemotherapeutic drugs, and preventing the body's resistance to the drugs.[28] One of the studies[29] showed that in just 72 hours, the efficacy of treatment using chemotherapeutic drugs, such as Taxol and Adriamycin, with selenium yeast is significantly higher than the treatment using the drugs alone. The finding was shown in various cancer cells (breast, lung, small intestine, colon, liver).
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Old 01-18-2008, 11:30 AM   #4
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Re: Does anyone know what nutrients Paxil depletes?

I'm going to get some tests done shortly. I don't believe that anyone knows for sure which nutrients and minerals SSRIs deplete us of, but I'm pretty certain that they must create some imbalances. It might not be possible to get tests done with your doctor and you may well have to go to see a nutritionist privately. I think elevated copper levels and other metals are the ones to look out for as well as low folate and B12.
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Old 01-18-2008, 11:36 AM   #5
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Re: Does anyone know what nutrients Paxil depletes?

All drugs, including asprin, deplete nutrients.
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Old 01-18-2008, 11:38 AM   #6
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Re: Does anyone know what nutrients Paxil depletes?

On Paxil my tests came out relatively normal, but in withdrawal my iron levels depleted severely. I still haven't checked out my thyroid, but I feel like I should.
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Old 01-18-2008, 11:39 AM   #7
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Re: Does anyone know what nutrients Paxil depletes?

Quote:
Originally Posted by Bern View Post
I looked up Selenium on wikipedia.....http://en.wikipedia.org/wiki/Selenium
This is what I found.....

The main action of selenium is it helps , or should I say ..especially helps the detox process, especially in the brain. The is still though controversy whether selenium supplements affect the pancreas and the function of insulin, so I would say..in moderation.

Laurie's list is very good , you might wan to consider higher levels of C
, I use up to 6,000 Mgs and also use a gamut of herbs to help my immune function.

Regards, Johnny
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Old 01-18-2008, 03:20 PM   #8
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Re: Does anyone know what nutrients Paxil depletes?

It depletes Glutathoine, which is needed for immune system function.
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Started Paxil 2000 for post partem anxiety
Happily on it until it pooped out 2/07
Started cutting down way too fast 7/07
from 20 mg. to 10 mg. and got very sick.
Found PP, went back to 13 mg.
Waited and waited and never stablized.
Began slow wean, down to 7 mg. over a year. Never felt well.
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Old 01-19-2008, 07:21 AM   #9
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Re: Does anyone know what nutrients Paxil depletes?

I noticed there is a new line of Nature Made(?) vitamins for people who take medications, and there is one specifically for people who take anti-depressants. It has Folic Acid, Vitamins B and D among other things.
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Old 01-19-2008, 08:02 AM   #10
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Re: Does anyone know what nutrients Paxil depletes?

Some good tips on this site about ssri's and supplements.

After your reaction to an (SSRI/SSNRI) Anti-Depressant

The first 3-18 months

One of the long term side-effects after experiencing a reaction to an (SSRI) antidepressant, is an extreme hyper-sensitivity of the nervous system to light, sound, supplements, herbs and fabricated synthetic vitamins. Furthermore physical symptoms such as muscle tightness, electrical shocks through the brain and the body, feelings of burning on the surface or inside of the skin (deregulation of pain perception), visual and/or auditory hallucinations, as well as emotional and psychological problems. For a more detailed discussion regarding above mentioned side-effects click here.

We do not recommend to expose your body to synthetic chemicals whilst experiencing more or less severe hypersensitivity of the nervous system. We rather recommend to get your essential elements from preferably organic low acid food. Low acidic foods have a high pH value which is ALKALINE or BASIC! You need to 'alkalinize' your system (body) above a pH value of '7' !

Eat enough fruit and vegetables in a variable alkalinizing balanced diet, and drink lots of water. For instance tomatoes, bananas, kiwi's, broccoli, aloe vera, carrots, cabbage, beans, cucumbers, etc., are a very rich source of essential minerals, vitamins and amino acids. Do not take 5-HTP to create more serotonin in your brain. By simply leaving your serotonergic neural system alone, you will assist it the most to find it's own natural balance again. Unfortunately this will take some time.

Do not charge your nervous system like you always did before your reaction to an (SSRI) antidepressant. If you charge your nervous system too much, like too much stress, a surgery, unhealthy eating patterns, etc., you actually delay your recovery. You will have to learn to listen to your body, what means that you know when to withdraw and when to get active.

When you suffered a reaction to an (SSRI) antidepressant your nervous system becomes hyper-sensitive to ALL stimuli. What are stimuli? It is everything that acts on your nervous system (directly or indirectly) like light, sound, but also violence on TV, stressors, certain supplements or fabricated vitamins, etc. All these things act as stimulants to your nervous system. Actually the effects of a psychoactive drug and watching a horror movie are very much comparative to each other...that is: they BOTH act on your nervous system!

The key solution to recovery is NOT to stimulate your nervous system, but, to sedate your nervous system. Every time when you stimulate a nervous system that in fact needs to be sedated to recover, you delay the process of healing. We know it will be impossible to lock your self up in a dark, silent room and this is definitely not what we are trying to say. You just have to learn when to withdraw yourself (and thus your nervous system) from stimuli and when to come out.

Consider sweat baths (sauna baths). This is a very healthy habit. Sweat baths are extremely sedating to the nervous system. When you take a sweat bath on a regular base this will strengthen your cardiovascular system and improve the blood circulation. Next to this, go out in nature, trees, green, oxygen, gentle walking, etc..

About taking supplements

We learned that everyone who is experiencing (SSRI) antidepressant side-effects, is looking for the quick relief. People are experimenting with whatever supplement or fabricated synthetic vitamin they can get their hands on. Simply avoid this if that is possible.

As previously mentioned above, we do not recommend to expose your body to synthetic chemicals whilst experiencing more or less severe hypersensitivity of the nervous system. We rather recommend to get your essential elements from preferably organic low acid food in a variable balanced diet.

Two to three simple bananas and kiwi's, an egg-sandwich, 2-3 glasses of milk, a few tomatoes and an avocado a day provides many of the essential vitamins, (trace)minerals & amino acids you need on a daily base. Vegetables especially rich in essential elements are: Peas, Potatoes, Broccoli, Squash (Summer), Spinach, Lima Beans & Kale. The taste of nature is nice and it saves you money on unnecessary supplements too!

However we also understand that getting your essentials from a variable diet requires some skills in preparation and cooking of your daily meal. Not everyone is able or willing to do that. In that case you need to add your essential elements otherwise. We understand if you feel the need to take a daily multi-vitamin complex. There are many different multi-vitamin complex products, unfortunately a lot of rubbish amongst them. Most of them contain extra added synthetic chemicals which you must avoid. If you are going to take a multi-vitamin complex you need to be aware of the following:

make sure that it doesn't contain Vitamin K. Vitamin K plays a role in the manufacture of blood clotting. Too much of this vitamin might interact with plasma serotonin which is also known to make blood form cloths (see article, "2.a. Serotonergic functioning"). Although there is more research needed regarding this matter, the anecdotal reports of (former) (SSRI) antidepressant users imply fabricated vitamin K as a cause for the worsening of their already exisiting symptoms.

make sure that ALL B-vitamins are low(never above the daily recommended standard). It is important to note that most B-vitamins work as stimulants to the nervous system. You need to avoid that.

make sure that the B3 compound is as niacinamide and NEVER as niacine (this will give a flush which could make you re-live all of your symptoms again).
Depending on the severeness of the reaction you experienced to an (SSRI) antidepressant we also recommend that if you decide to take your essential elements otherwise, to take calcium/magnesium/zinc in a vegetarian formula. Never exceed the daily dose of Calcium 1000mg, Magnesium 400mg and Zinc 15mg. Although calcium/magnesium/zinc are not known to act as stimulants, caution is needed. Always start with small amounts (1/6 of the daily dose), gradually build up and keep monitoring yourself.
In these first 3-18 months the cycles or the emotional rollercoasters (the tricks your brain is playing on you) can be extremely frightening. And it will seem like it never ends, especially when you find a bit of hope in the evening to be back at square one in the morning. Be firm! We all understand its the most frustrating experience right now for you. It's serotonin related and that's why you are experiencing delayed (withdrawal) side effects and flashbacks, but gradually it will get better. Evaluate your recovery by weeks and months, not days.

You are going to experience minutes, hours and days that you will start to feel better. The cycles will get longer in duration and eventually you will have more good then bad days. Though, it is most important you also treat your nervous system with care during these better days. Don't think when the better days arrive that you can charge your nervous system like you always did before. It will give you a major set-back! Stick to the list we provide you below, on how to assist your recovery during this period.

Friends and Family

These times are very tough to experience. Your friends and family cannot even imagine the powerful influence these drugs have on your mind and your sub-consciousness. They simply cannot believe that these drugs can have such a powerful effect on someone's brain. You might loose your trust in them after this. Try to accept and understand their ignorant and frustrating reactions. Avoid them for a while, if that's possible.


How can I assist my recovery during this period?

Avoid any psycho-stimulants such as medications, herbs, but especially: violence on TV. Why? Because right now your nervous system has become hyper-sensitive and extremely susceptible to every input from your surroundings, not only light and sound! You must also protect your sub-consciousness until you reach a level of emotional stability.
Ingest low acid foods and try to minimize the ingestion of high acidic foods with a low pH-grade! REMEMBER: You need to 'alkalinize' your system (body) above a pH value of '7' !

Avoid Grapefruit Juice. Grapefruit juice is an inhibitor of the cytochrome P-450 enzymes. These enzymes are known to metabolise (break down) (SSRI) antidepressants in the liver. Drinking grapefruit juice whilst you are taking an (SSRI) antidepressant can create a serious toxic reaction, because the (SSRI) antidepressant will build to toxic levels in the bloodstream! For more information click here.
No caffeine. Drink lots of chamomile tea, sweetened with honey.

No alcohol.

Don't take Saint John's Worth. St. John's Worth works more or less as a natural SSRI (on post synaptic receptors), also interacting with your serotonergic neural system

Don't take Ma-Huang (Ephedra) because it's a powerful adrenalin (epinephrine) stimulant, triggering adrenalin rushes.

Don't take Kava Kava, it can intensify (SSRI) antidepressant (withdrawal) side-effects or give flashbacks to previous side-effects you experienced.
Eat neutral alkaloids, vegetables, etc..

Don't do any intensive exercise like jogging or aerobics, but instead try meditation, gentle stretching, gentle walking.

Go out in Nature, or go to a Sauna, or whatever environment where you may find a little peace of mind and body.

Listen to light Classic music or New Age music, watch cartoons (or anything else without violence), go walking, take hot or cold showers, anything that might work for you, anything to "manage" the "twilight zone" of suicidal and offensive thoughts and dissociated emotions.

Focus on memories of events in your past (like childhood memories) which will recall positive emotions. Hang on to them!

Learn during this period, which thought or view will give you any positive emotional response and write this down into the form of an affirmation! Read these affirmations for yourself every morning when you wake up! In this way you will slightly re-program your brain to tune into positive emotions.

Time and Nature will be your best friends in your healing process. In this battle you don't fight to win because you can't. You simply will survive it. Focus on the thought to survive this, and you will, just as other individuals did. Don't force yourself to become the person again that you were before this, but make a statement to yourself that you will come out of this "trip." Make this statement to your self everyday, every hour.

Whilst You are Recovering...

We strongly persist not to take any supplements, herbs and/or synthetic vitamins until your nervous system has strengthened over time. Continue to ingest proper food, vegetables and fruit during this period. Treat your nervous system with care. As mentioned above: don't think when the better days arrive that you can charge your nervous system like you always did before. It will give you a major set-back! Be careful and monitor your body closely whilst you are ingesting a supplement or herb.

http://www.antidepressantsfacts.com/reaction.htm
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Old 01-19-2008, 08:40 AM   #11
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Re: Does anyone know what nutrients Paxil depletes?

Please, everyone read this last post on Antidepressant Facts. It's one of the best places to go as a starting point. I stopped doing anything to take care of myself while on Paxil, and everything stemming from the last three years, when I started Paxil CR -- no vitamins, nothing, and eating badly, and I had that nasty desire to drink beer -- started out as one a day and then two and was heading towards three a day by the time I got off. So I went from being a virtual non-drinker to drinking everyday. I wonder if this self-destructive behavior has helped to fuel my prolonged withdrawal (besides the CT), as I've had to play "catch-up" with the supplementation and, of course, staying away from the B vitamins. I've only recently added a Women's multi and I'm only taking half the recommended dosage because of the amount of B vitamins.

Selenium is an interesting suggestion, especially when it comes to the eyes. I've had a problem with my left eye since my early 20s, obviously more than 20 years before I ever touched an SSRI. I don't remember the name of it, but in the good old days when I had health insurance this problem was studied extensively at New York University Hospital. It was basically a buildup of fluid in the retina and my central vision would have a very distinct black spot when I looked at a paper. I always new one of these episodes was coming on because I could feel the distorted vision. It was determined to be something viral and possibly caused by stress. Anyway, my doctor, Dr. Chang, recommended selenium supplementation. Sadly, I've had many episodes still and I have permanent scarring in my retina on the left.

I am taking a selenium supplement now and have been for the past several months, not just for the eyes, but to also aid in the absorption of the Omega oil. I still have the floaters in both eyes. The one in my left started in 2004 and the one in my right started within a couple of months of being off Paxil.

So, those of you weaning or still on Paxil or any other SSRI, take your vitamins as recommended as that article. You may be very lucky and be ahead of the game in your recovery.
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Zoloft 150 mg. June '97, CT September '97, 2 wks brain zaps, then fine. Prescribed for "the blues"
September '99 Paxil 20 mg - for life problems
Switched Paxil CR 2004
CR 2005 recalled
Switch generic Paroxotine
2003 start poop-out
April 21, 2006 CT
Off Paxil since April 21, 2006
ADVICE: NEVER CT

Am I better? I got through the worst of worst in three years. Still living with the damage, financial, creative and otherwise, that Paxil left me with.
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Old 01-19-2008, 09:23 AM   #12
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Re: Does anyone know what nutrients Paxil depletes?

Here is a good table with the toxic affects of taking too much synthetic vitamins. Be careful, concentrated synthetic vitamins act as drugs in the body and can be toxic.

http://www.1stholistic.com/Nutrition...ic-dosages.htm

How to get nutrients from real food.

http://whfoods.org/foodadvisor.php

http://whfoods.org/nutrientstoc.php
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Old 01-19-2008, 09:31 AM   #13
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Re: Does anyone know what nutrients Paxil depletes?

Quote:
Originally Posted by Johnnny off Paxil View Post

you might wan to consider higher levels of C
, I use up to 6,000 Mgs and also use a gamut of herbs to help my immune function.
This is not a good idea. Chronic ingestion of high doses of vitamin C will make you sick!

Vitamin C, chronic

3 gm

Increased urinary oxalate and uric acid levels in rare cases, impaired carotene utilization, chelation (binding of vitamin C with minerals) and resultant loss of minerals may occur, sudden discontinuation can cause rebound scurvy. Kidney and bladder stones, urinary tract irritation, increased tendency for blood to clot, breakdown of red blood cells in persons with certain common genetic disorders (such as glucose-6-phosphate dehydrogenase deficiency, common in persons of African origin), may induce B12 deficiency.

http://www.1stholistic.com/Nutrition...ic-dosages.htm

No one should take high doses of any "vitamin" without the supervision of a qualified health care provider who understands what these "supplements" can do to a person if used incorrectly and at toxic doses. Synthetic, concentrated vitamins and supplements act as drugs within the body and should be treated as such.
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