Not responding to drugs (can anyone relate)

mlynch · 03-08-2009, 11:50 PM

Alcohol, caffiene, my adderall prescription, barely effect me anymore. This isn't even tolerance related. I used to get instantaneous and profound effects from all of these, no longer how long I took them I was just a freaking light-weight.

I'm 140 pounds 5'11, and now post ssri I'm able to drink a pint of 80 proof vodka in a span of 3-4 hours and I'll have a solid buzz going and that's it.. It's rather amusing to see other people scratching their heads thinking I'm an alcoholic when I barely drink at all. (... like there's even a point anymore??)... I am noticing these effects post ssri use...it's like my synapses are just burned out or something

daisy232627 · 03-09-2009, 02:29 AM

I have had this off and on when it comes to the drinking and caffiene but, boy when its on, it really kicks my a**!! I tend to avoid both most of the time and I don't handle hang-overs well at all!!! Sorry I'm not more help!

been there done that · 03-09-2009, 04:17 AM

Sounds like how I was in pooped out but that sure changed when I ct it was the opposite big time still can't tolerate a large coffee. One small one once in a while is my limit.
I did think that all the drugs I was on mostly antibiotics were not making any difference at all or if they did it was breif and I would need another in a wk or two at the most.
You don't say what you are withdrawing from or how much you were on??? could you post that please as I am curious. thanks

Wurstbrot · 03-09-2009, 01:52 PM

Mlynch, they do effect you. I would avoid those quantities in w/d, it can give you a major crash!
Keep in mind that your liver probably is not working properly these days.
Many of us here went into the alcohol trap, because of the cravings.
I think it has to do with the overstimulation from the SSRI. Your brain crys for balance. If someone takes cocain, he can drink hudge quantities of alcohol, too. If you drink more alcohol, you need to smoke more cigarettes and so on..

scotia21 · 03-09-2009, 02:23 PM

Are you taking an SSRI now? When I was on Paxil I could drink and drink and drink and barely get buzzed - and I never had a hangover either. It's not that way anymore. I can't even have one drink now without feeling like poo for days afterwards.

Katesmom · 03-09-2009, 02:55 PM

Whether you feel it or not, your liver still has to deal with it. It is possible that something is going on with the metabolization of these things inside your liver that could be w/d related.

been there done that · 03-09-2009, 05:50 PM

Quote:

Originally Posted by Wurstbrot

Mlynch, they do effect you. I would avoid those quantities in w/d, it can give you a major crash!
Keep in mind that your liver probably is not working properly these days.
Many of us here went into the alcohol trap, because of the cravings.
I think it has to do with the overstimulation from the SSRI. Your brain crys for balance. If someone takes cocain, he can drink hudge quantities of alcohol, too. If you drink more alcohol, you need to smoke more cigarettes and so on..

Could you tell me what drinking more alcohol has to do with needing to smoke more cigarettes?
My freind who died of the stroke shortly after starting celexa had a horrible head ache and had already fallen once when I arrived at this apartment one thing I noticed just before his next two drops and the end of his life was that he was smoking one cigarette after the other. He was also taking aspirin and I would like to tell people on here please do not take aspirin if you are taking celexa. He had a massive cerebral hemohage later that day had surgery but it didnt' save him. He is dead. I am wondering if the celexa and asprin together did something to cause him to try to regulate his brain chemistry with smoking????

For myself could drink a ton of coffee while on ads and not stay awake or get shakey I was addicted to coffee bad.

mlynch · 03-09-2009, 11:24 PM

When I was on meds everything would effect me 100000 times, when I withdrew I was ultra sensitive. As time went on that feeling went away and now I feel flat all the time and I don't feel anxiety and my adderall prescription that has consistently worked for me since freaking middle school barely effects me anymore. (along with every other drug) This is seriously bull****, i've been off all these stupid drugs since 2005. Paxil..lexapro....abilify...then prozac. This was all through high school. I'm starting to think taking these drugs when my brain was still developing really ****ed me over for good. This bull**** never ends. All I want to do is to sit in a chair, stair at a wall and just wait to ****ing die...just take me.

granturissimus · 03-09-2009, 11:34 PM

im on an SSRI right now and i too can drink alot without even getting a buzz. it wasnt like that when i got on my meds originally, everything worked normal back then, but after i quit and restarted i get this strange inability to get drunk.

Songbird · 03-10-2009, 12:45 AM

Which SSRI were you on? When I first went on paxil I found I became intoxicated on a much smaller amount of alcohol and my p-doc told me it is because alcohol and paxil use the same liver enzyme. So after being on it for a while perhaps the liver produced more of that enzyme...

mlynch · 03-10-2009, 04:09 AM

umm..after doing some extensive research I have realized that fish oil could be a potential culprit for both my unbearably emotionless state (much worse then usual) and my inability to be effected by drugs. I'm trying to think of what has happened during the time I have noticed these symptoms and I thought fish oil would be the last thing that would cause these symptoms, but I am coming across people who say that it makes them purely emotionless, it also raises liver enzymes which would explain how my effectiveness for drugs is inhibited. This is just a theory.. I can't trust anything now.. I mean I was pretty emotionless after ssri's but recently it's gotten much worse along with the drug tolerance issues...so maybe it's not the ssri's who the hell knows

03-08-2009, 11:50 PM	#1
mlynch Join Date: Mar 2007 Posts: 53	Not responding to drugs (can anyone relate) Alcohol, caffiene, my adderall prescription, barely effect me anymore. This isn't even tolerance related. I used to get instantaneous and profound effects from all of these, no longer how long I took them I was just a freaking light-weight. I'm 140 pounds 5'11, and now post ssri I'm able to drink a pint of 80 proof vodka in a span of 3-4 hours and I'll have a solid buzz going and that's it.. It's rather amusing to see other people scratching their heads thinking I'm an alcoholic when I barely drink at all. (... like there's even a point anymore??)... I am noticing these effects post ssri use...it's like my synapses are just burned out or something

03-09-2009, 02:29 AM	#2
daisy232627 Join Date: Jun 2005 Location: dallas, texas Posts: 226	Re: Not responding to drugs (can anyone relate) I have had this off and on when it comes to the drinking and caffiene but, boy when its on, it really kicks my a**!! I tend to avoid both most of the time and I don't handle hang-overs well at all!!! Sorry I'm not more help! __________________ started Paxil 20mg 07/01 weaned 3mo Paxil free 08/02 back on 10/02 for panic/anxiety tried wean again 05/03 too quick failed under doc's instructions (didn't know it was too quick, I thought I was just screwed for life) tried to wean again sometime prior to finding pp-still thinking I'm screwed 06/03 Paxil CR 25mgs 2004 changed to generic 20mg costs less 03/06 back to Paxil CR 25mg-Panic/anxiety 01/2008 start weaning AGAIN 03/2009 Paxil 10mg

03-09-2009, 04:17 AM	#3
been there done that Banned Join Date: Jul 2008 Location: Canada Posts: 1,856	Re: Not responding to drugs (can anyone relate) Sounds like how I was in pooped out but that sure changed when I ct it was the opposite big time still can't tolerate a large coffee. One small one once in a while is my limit. I did think that all the drugs I was on mostly antibiotics were not making any difference at all or if they did it was breif and I would need another in a wk or two at the most. You don't say what you are withdrawing from or how much you were on??? could you post that please as I am curious. thanks

03-09-2009, 01:52 PM	#4
Wurstbrot Join Date: Oct 2008 Location: Austria Posts: 164	Re: Not responding to drugs (can anyone relate) Mlynch, they do effect you. I would avoid those quantities in w/d, it can give you a major crash! Keep in mind that your liver probably is not working properly these days. Many of us here went into the alcohol trap, because of the cravings. I think it has to do with the overstimulation from the SSRI. Your brain crys for balance. If someone takes cocain, he can drink hudge quantities of alcohol, too. If you drink more alcohol, you need to smoke more cigarettes and so on.. __________________ 7 years Paxil 40mg Tapered 10 months: 10mg to 0mg in 3 months 10mgs every other day/week 2008 free 1-3 mild symptoms 3-10 deep hell, 1 week peace 10-11 deeper hell, 10: found PP 1 week fine 11-12 nearly 2 months mild & tolerable 12-14 bad wave, 3 days peace, chest pain, 2 weeks later 14-15 emotional breakdown and back into the worst ever 15: back alive! 18: back to work m22.... We gonna work this shizzle out! Good Must Always Win Over Evil.

03-09-2009, 02:23 PM	#5
scotia21 Join Date: Nov 2006 Location: Oklahoma Posts: 5,419	Re: Not responding to drugs (can anyone relate) Are you taking an SSRI now? When I was on Paxil I could drink and drink and drink and barely get buzzed - and I never had a hangover either. It's not that way anymore. I can't even have one drink now without feeling like poo for days afterwards. __________________ 1/05/07 20mg-17.5 1/20 17.5-15 2/24 15-12.5 3/08 12.5-10 3/29 10-7.5 4/12 7.5-5 6/15 5-3.75 6/30 3.75-2.5 7/28 2.5-1.5ish 8/11 1.5-1 8/25 1- zero "Keep lighting candles, eventually nobody will be in the dark" me "Why is it so hard for everybody to believe that a pill can change brain chemistry for the better but not for the worse?" me "Time does not come in pill form" me

03-09-2009, 02:55 PM	#6
Katesmom Moderator Join Date: Jul 2005 Location: Texas Posts: 13,706	Re: Not responding to drugs (can anyone relate) Whether you feel it or not, your liver still has to deal with it. It is possible that something is going on with the metabolization of these things inside your liver that could be w/d related. __________________ Katesmom aka Kim started Paxil Oct. 2003 for PIH Paxil free since 19 Jul 2005 ". . .the cruelest lies are often told without a word. . .the kindest truths are often spoken, never heard." -- Ben Folds

03-09-2009, 11:24 PM	#8
mlynch Join Date: Mar 2007 Posts: 53	Re: Not responding to drugs (can anyone relate) When I was on meds everything would effect me 100000 times, when I withdrew I was ultra sensitive. As time went on that feeling went away and now I feel flat all the time and I don't feel anxiety and my adderall prescription that has consistently worked for me since freaking middle school barely effects me anymore. (along with every other drug) This is seriously bull**, i've been off all these stupid drugs since 2005. Paxil..lexapro....abilify...then prozac. This was all through high school. I'm starting to think taking these drugs when my brain was still developing really ed me over for good. This bull never ends. All I want to do is to sit in a chair, stair at a wall and just wait to **ing die...just take me.

03-09-2009, 11:34 PM	#9
granturissimus Join Date: Dec 2008 Location: Los Angeles, CA Posts: 358	Re: Not responding to drugs (can anyone relate) im on an SSRI right now and i too can drink alot without even getting a buzz. it wasnt like that when i got on my meds originally, everything worked normal back then, but after i quit and restarted i get this strange inability to get drunk. __________________ Yuriy Dec 07 failed lexapro taper... severe OCD+anxiety as withdrawal Mar 08 started 200mg zoloft... severe weightloss Apr 08 started paxil 60mg... severe depression+hairloss May 08 started lexapro 20mg... severe akathisia Dec 08 started celexa 60mg... most stable Found PP Celexa -01/07 40 -01/23 30 -02/13 25 -03/06 20 -03/27 18 -04/17 16 -05/08 14 -05/29 12 -06/19 9 -07/03 7 -07/26 6 -08/16 5 -09/07 4.5 -11/13 4.4

03-10-2009, 12:45 AM	#10
Songbird Join Date: May 2007 Location: New Zealand Posts: 7,046	Re: Not responding to drugs (can anyone relate) Which SSRI were you on? When I first went on paxil I found I became intoxicated on a much smaller amount of alcohol and my p-doc told me it is because alcohol and paxil use the same liver enzyme. So after being on it for a while perhaps the liver produced more of that enzyme... __________________ Jul 01-Feb 02 Aropax Feb - Dec 03 Citalopram Jul 04 Aropax Jan 07 - Feb 08 20mg - 5mg Apr 4.5mg 5mg Jun 10mg zopiclone > seroquel Jul 20mg Aug + methionine Oct aropax > loxamine Dec off seroquel 7 Dec 17.5mg 30 Dec 15mg 24 Jan 12.5mg 16 Feb 10mg 10 May 9mg 30 May 8mg 5 July 7.5mg 2 Aug 7.25mg 1 Sep 7mg 9 Oct 6.75mg 8 Nov 6.5mg Appreciation is the antidote to stress - Trust is the antidote to fear

03-10-2009, 04:09 AM	#11
mlynch Join Date: Mar 2007 Posts: 53	Re: Not responding to drugs (can anyone relate) umm..after doing some extensive research I have realized that fish oil could be a potential culprit for both my unbearably emotionless state (much worse then usual) and my inability to be effected by drugs. I'm trying to think of what has happened during the time I have noticed these symptoms and I thought fish oil would be the last thing that would cause these symptoms, but I am coming across people who say that it makes them purely emotionless, it also raises liver enzymes which would explain how my effectiveness for drugs is inhibited. This is just a theory.. I can't trust anything now.. I mean I was pretty emotionless after ssri's but recently it's gotten much worse along with the drug tolerance issues...so maybe it's not the ssri's who the hell knows

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