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Paxil and Withdrawal FAQ-Updated 4/2008 *** READ ONLY *** The net's best Frequently Asked Questions and answers on all things Paxil and Paxil Withdrawal. NEW MEMBERS SHOULD START HERE

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Old 12-13-2004, 10:43 AM   #1
Ariella
 
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About Paxil

This section will answer questions like What is Paxil? and Where did it come from?
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002
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Old 12-13-2004, 10:44 AM   #2
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What is Paxil?

Paroxetine (Paxil in North America, Seroxat in the UK and Aropax in Australia) is an SSRI used principally to treat mood affective disorders. Approved by the United States Food and Drug Administration of the Department of Health and Human Services (FDA) in 1992 to treat anxiety related conditions, paxilprogress visitors have shared numerous other reasons for having it prescribed to them, which include intermittent, post partum and long term depressions, Obsessive Compulsive Disorder (OCD), Premenstrual Syndrome (PMS), Fibromyalgia, Attention Deficit Disorder (ADD), thyroid irregularities, head injuries, eating disorders and more. This is not a complete list. Doctors have been free to develop new uses for their patients, including the relief of headaches. A drug that potentially affects your mood, personality, appetite, sleep habits and interest in sex has actually been prescribed for temporary pain relief.
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002
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Old 12-13-2004, 10:45 AM   #3
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Where did Paxil come from?

Paxil can be considered the multi generational offspring of many other medications that date back as far as the end of the 19th century. Some of its ancestors include cocaine, tricyclics, monoamine oxidase inhibitors (MAOI) and the popular SSRI fluoxetine (Prozac). Often referred to as a me too drug (implying a competitive marketing strategy against other medications), Paxilís manufacturer GlaxoSmithKline (GSK) marketed it as being even more selective then other antidepressants.
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002
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Old 12-13-2004, 10:45 AM   #4
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What is Paxil's half-life (and what is that) ?

Paxil has a half-life of less than 24 hours. This means that Paxil is a substance that your body actively seeks to remove and it takes less then a day for your body to reduce the concentration of Paxilís active agents in your blood by about half. This is a short half-life compared to Prozac, which has a half-life of more than a week. We believe the shorter half-life of Paxil contributes to the potential for withdrawal symptoms. The body is used to being in control and making gradual changes. A drug with a short half-life will rock your world as your body scrambles to adjust.
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Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002
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Old 12-13-2004, 10:46 AM   #5
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Is Paxil addicting?

In 2002, the american legal system debated the definition of the world addiction as it pertains to Paxil.

For a drug to be labelled habit forming, you have to demonstrate a drug seeking behavior often at the expense of rationality, safety, and economic feasibility. This means you have to be highly desiring of the drug for the sake of having the drug. This isnít quite the case with Paxil. Our own withdrawal experience and anecdotal research tells us that people donít usually crave and dream about a colored pill lustfully enough to attempt to rob a bank, steal from a relative or sell a car. However, several people have been known to go to creative lengths to get more Paxil when their medical insurance runs out, including calling Paxil's manufacturer for free doses. This type of behavior is very similar to getting in touch with a pusher when you're out of money and/or out of product. Most people withdrawing from Paxil desire a relief from the withdrawal symptoms though. And hereís where the lines blur.

The definition of addiction describes how a participant may also seek a substance to avoid the withdrawal experience. This is like someone seeking cocaine because the depression of the down time is too great. Since Paxil withdrawal may include symptoms of depression, it sounds just like one facet of cocaine addiction.

And to confuse matters further are people who have learned to cope with life and its inherent challenges with a medication. They may feel like they have a predisposition towards using a drug to feel like a trouble-free human being. They may not know how to do it any other way. This kind of behavior reasons that a drug can be used to shorten a grieving period or to relieve an old fear. If it worked during the last two life hurdles, why wouldnít it for the third right?

Taking all this into account, we believe that Paxil is mostly a psychosocial addiction although it carries a physical burden through it's intense withdrawal experience. This drug has been prescribed for too many emotional inconveniences or to release people from personal accountability, where lifestyle and self-perception changes would serve better. Paxil is a symptom suppressant and too many people are taking it under the false assumption that it will cure their ills. This behavior is very addicting and it compliments rampant mechanisms such as overeating and compulsive shopping. Running to pills is becoming a way of life, as direct to consumer advertising crafts everyone's mindshare/filter of the world around them.
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002

Last edited by elisa : 12-13-2004 at 03:29 PM.
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Old 12-13-2004, 10:48 AM   #6
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What does Paxil do with serotonin?

When neurotransmitters send a message with serotonin, some of it is gobbled back up before reaching its destination. Itís like selective censoring or dumping hundreds of marbles quickly into your hand. Your hand catches some of them, and the others continue their journey to the floor. Paxil takes away your hand so that they all hit the floor. In other words, Paxil stops the reabsorption of serotonin back into the transmitter that sent it. As the drug family name that Paxil is in suggests, Paxil is a Selective Serotonin Reuptake Inhibitor (SSRI). It stops your transmitters from reuptaking (taking back) what it sends out. By inhibiting the natural reabsorption process, your brainís receptors get a more generous helping of serotonin.

The body didnít evolve to always mess things up. Itís actually designed to try to balance things, be well and not work so hard. Life and stress will certainly challenge it and upset its balance, but it prefers to sleep in at least once in a while. To me it seems that using Paxil is a gamble that the flood of serotonin it causes will be in the right amount, at just the right time that youíll somehow feel better, while circumventing any chance your body has to figure it out. Whatever the result, withdrawal involves an attempt on your bodyís part to get back under the scale and it may tip one way to the other until itís chemically satisfied. This process can feel uncomfortable and take months.
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002
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Old 12-13-2004, 10:51 AM   #7
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How does taking Paxil affect daily life?

Since Paxil affects chemical communication in your body, your ability to perceive daily experiences or self identity can be affected.

Science is still learning how emotions and serotonin are linked, but personal experience is clear that one affects, or is derived from the other. While on Paxil, your potential to experience a wide range of emotions that run from frightening anger to passionate bliss is diminished. This influence on your emotions is the desired effect of Paxil since it can diminish your negative sensations so that you can become a more productive and less encumbered machine (or human). But it turns out that it’s not necessarily selective about what it diminishes. Your joyous passions and sex drive can also get put on a shelf. The body doesn't operate in a vacuum. When you change the serotonin level, you also change the balance of many other chemical processes in the body. It's not as simple as "raise the serotonin, feel wonderful".
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002

Last edited by scotty : 04-05-2008 at 05:31 PM.
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Old 12-13-2004, 10:53 AM   #8
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Does Paxil make people suicidal?

As of September 2004, Paxil labelling includes a black-box, the most serious warning a drug can carry short of being pulled from the market, that states that Paxil may cause suicidal ideations in people under the age of 25.

Obviously, if the earth spins around the sun once or twice more and a person becomes labelled as an adult, they are still at risk. New research helping to reveal this reality using the adult naming convention/vocabulary has recently come to light.
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002

Last edited by scotty : 04-05-2008 at 08:34 AM.
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Old 12-13-2004, 11:11 AM   #9
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Does Paxil have any side effects?

Besides having a potential to zombify, repress, and trigger suicidal ideations, it can also make you anxious, depressed, nonchalant, indifferent, uncaring, cold, agitated, twitchy, and your ears ring. On top of those popular ones are:

Somnolence
Insomnia
Agitation
Tremor
Dizziness
Nervousness
Headache
AstheniaPalpitation
Vasodilation
Constipation
Nausea
Diarrhea
Dry mouth
Vomiting
Flatulence
Abnormal ejaculation
Sweating
Impotence
Libido Decreased
Rash
Decreased Appetite
Oropharynx Disorder
Dyspepsia
Myalgia
Myasthenia
Paresthesia
Drugged Feeling
Confusion
Respiration Yawn
Blurred Vision
Taste Perversion
Urinary Frequency
Abdominal Pain
Back pain
Chest pain
Dysphagia
Eructation
Gastritis
Gastroenteritis
Gingivitis
Glossitis
Increased salivation
Rectal hemorrhage
Ulcerative stomatitis
Amenorrhea
Breast pain
Cystitis
Dysuria
Hematuria
Menorrhagia
Nocturia
Polyuria
Urinary incontinence
Urinary retention
Urinary urgency
Vaginal moniliasis
Vaginitis
Breast atrophy
Breast enlargement
Endometrial disorder
Epididymitis
Neuralgia
Neuropathy
Nystagmus
Peripheral neuritis
Psychotic depression
Reflexes decreased
Reflexes increased
Stupor
Torticollis
Trismus
Bloody diarrhea
Bulimia
Cholelithiasis
Duodenitis
Enteritis
Esophagitis
Fecal impactions
Fecal incontinence
Gum hemorrhage
Hematemesis
Hepatitis
Ileus
Intestinal obstruction
Jaundice
Melena
Mouth ulceration
Peptic ulcer
Stomatitis
Tongue discoloration
Tongue edema
Tooth caries
Diabetes Mellitus
Goiter
Hyperthyroidism
Hypothyroidism
Thyroiditis
Anemia
Eosinophilia
Leukocytosis
Leukopenia
Lymphadenopathy
Purpura
Abnormal erythrocytes
Basophilia
Bleeding time increased
Hypochromic anemia
Iron deficiency
Flu like symptoms
Lump in throat
Anorgasmia
Erectile Difficulties
Chills
Dyspepsia
Abnormal dreams
Impaired concentration
Depersonalization
Amnesia
System Pharyngitis
Sinusitis
Malaise
Face Edema
Moniliasis
Neck pain
Adrenergic
Female lactation
Fibrocystic breast
Kidney calculus
Kidney pain
Leukorrhea
Mastitis
Metrorrhagia
Nephritis
Oliguria
Pyuria
Urethritis
Voice alteration
Acne
Alopecia
Contact dermatitis
Dry skin
Ecchymosis
Eczema
Furunculosis
Syndrome
Cellulitis
Neck rigidity
Pelvic pain
Peritonitis
Ulcer
Tachycardia
Bradycardia
Hematoma
Migraines
Syncope
Angina pectoris
Arrhythmia nodal
Atrial fibrillation
Bundle branch block
Cerebral ischemia
Cerebrovascular accident
Congestive heart failure
Heart block
Low cardiac output
Myocardial infarct
Myocardial ischemia
Pallor
Phlebitis
Pulmonary embolus
Thrombosis
Varicose vein
Vascular headache
Ventricular Extrasystoles
Bruxism
Colitis
Lymphedema
Abnormal lymphocytes
Edema
Peripheral edema
SGOT increased
SGPT increased
Thirst
Bilirubinemia
BUN increased
Gout
Hypercalcemia
Hypercholesteremia
Hyperglycemia
Uterine spasm
Urolith
Vaginal hemorrhage
Priapism
Bradykinesia,
Cogwheel rigidity
Dystonia
Hypertonia
Abnormal gait
Akinesia
Antisocial reaction
Aphasia
Choreoathetosis
Circumoral paresthesias
Convulsion
Delusions
Diplopia
Drug dependence
Dysarthria
Extrapyramidal syndrome
Fasciculations
Grand mal convulsion
Hyperalgesia
Hysteria
Manic-depressive reaction
Meningitis
Myelitis
Hirsutism
Hyperkalemia
Hyperphosphatemia
Hypocalcemia
Hypoglycemia
Hypokalemia
Hyponatremia
Ketosis
Arthritis
Arthrosis
Bursitis
Myositis
Osteoporosis
Generalized spasm
Tenosynovitis
Tetany
Emotional lability
Vertigo
Abnormal thinking
Alcohol abuse
Ataxia
Delirium
Dystonia
Dyskinesia
Euphoria
Hallucinations
Hostility
Hypertonia
Hypesthesia
Hypokinesia
Incoordination
Seborrhea
Skin discoloration
Skin hypertrophy
Skin ulcer
Sweating decreased
Lack of emotion
Libido increased
Manic reaction
Neurosis
Paralysis
Paranoid reaction
Psychosis
Vesiculobullous rash
Herpes simplex
Maculopapular
Rash
Photosensitivity
Urticaria
Angioedema
Fungal dermatitis
Herpes zoster
Lymphocytosis
Microcytic anemia
Monocytosis
Normocytic anemia
Thrombocythemia
Thrombocytopenia
Withdrawal syndrome
Asthma
Bronchitis
Dyspnea
Epistaxis
Hyperventilation
Pneumonia
Respiratory flu
Emphysema
Hemoptysis
Hiccups
Lung fibrosis
Pulmonary edema
Sputum increased


This list was obtained from a GSK written prescription information document: http://www.paxilprogress.org/pdf/us_paxil.pdf

This content has been taken out of context for ease of presentation, and is not indicative of any symptom you should expect or be directly worried about. The list includes side effects that were been observed by GSK during pre/post market evaluation of their product. Also note:
  1. We have removed statistical data that would be indicative of symptom frequency, for what condition (anxiety, depression, OCD etc.) and pre/post market status.
  2. The reported adverse events were classified using a standard COSTART-based Dictionary terminology.
  3. Data is derived from Treatment-Emergent Adverse Experience Incidence in Placebo-Controlled Clinical Trials.
This means that the symptoms listed are conditions reported but not necessarily caused by Paxil. They haven't been discredited completely either .
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002

Last edited by Ariella : 01-03-2005 at 05:59 PM.
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Old 01-07-2005, 11:52 AM   #10
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How long does it take to lose weight gained from Paxil?

It will take as long as it takes you to discover what works. :) So many variables are involved in managing weight, that trying to predict how you turn around this Paxil side effect is very difficult.

What we know from experience is that it ususally takes longer than it would for you to lose the same weight without having had any Paxil in your system. On top of all that, if you are fresh from a withdrawal experience, you may still be very stressed and having to face how weight management changes during times of duress alone. It's a complicated thing, but there's much you can do.

Diets don't work. You know that. So get busy deciding how you want to experience health for the rest of your life. Figure out with professional help what is a healthy weight for you, and make daily choices that make it possible. Decide to eat foods that encourage health, even if you know you can "get away" with other foods. Any time you try to get away with something, you are confusing your own self declaration so that "I want to be healthy" becomes "I want to be healthy, sort of, I guess". Just guess which inner dialog is better for feeling well. :)

Having said that, you may be exercising regularly, eating great, and still not lose Paxil related weight. In this situation, you just have to be patient. The more time spent without Paxil, the greater the ability you'll have to manage your weight in ways that are simple and familiar. Let time reveal the turning point to you.
__________________
Panic attacks started Dec/1996
Zoloft summer 1998 (quit CT after a few days - bad reaction)
10mg Paxil fall 1998 / 20mg Paxil winter 1999
10mg September 2000 / 5mg October 2000 / FREE November 2000
Intense Withdrawal symptoms well into 2001
Withdrawal symptoms freedom by 2002
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